From Rejuran to MAXellize CHX400/CPX300 – The Evolution of Skin Boosters

Introduction: The Ever-Changing World of Skin Aesthetics

The field of medical aesthetics never stands still. Each year, new formulations, new injectables, and new buzzwords emerge to capture the attention of both doctors and beauty enthusiasts. A decade ago, hyaluronic acid fillers dominated the conversation. Soon after, skin boosters such as Rejuran and Chanel Injection (NCTF 135HA) reshaped how we thought about skin health. Then came the rise of Exosomes—hailed as the future of regenerative medicine. More recently, Juvelook entered the stage, sparking interest as a long-term collagen stimulator.

Each of these treatments represents a milestone. They have been praised, discussed, and sometimes criticized. Patients across Asia, Europe, and the Middle East ask the same question every time a new name surfaces: “What makes this one different?”

Today, the same curiosity surrounds MAXellize CHX400 and CPX300. These new-generation skin boosters have been introduced as not just another addition to the injectable market, but as the next evolution—combining the strengths of Rejuran, Chanel Injection, Exosomes, and Juvelook into one comprehensive formula.

But is this claim justified? To understand that, let’s revisit the journey of each of these iconic treatments and discover why CHX400/CPX300 are being called the “all-in-one premium boosters.”

Rejuran: The Birth of PDRN-Based Regeneration

When Rejuran first launched, it was revolutionary. Its core ingredient, PDRN (Polydeoxyribonucleotide), derived from salmon DNA, became a buzzword in clinics across Asia. The science was fascinating—PDRN worked at a cellular level to promote tissue repair, improve elasticity, and accelerate healing. Doctors found it especially useful for patients with damaged or aging skin, acne scars, and even those undergoing laser treatments.

Strengths:

• Focus on regeneration and healing

• Improves skin elasticity and texture

• Backed by strong clinical evidence

Limitations:

• Does not significantly brighten or whiten skin

• Lacks hydration effect

• Requires multiple sessions for visible improvement

Rejuran was often described as “medicine for the skin.” Yet patients who desired not just healing, but also glow, hydration, and radiance, had to look elsewhere.

Chanel Injection (NCTF 135HA): The Multivitamin Cocktail

If Rejuran was the doctor’s prescription, Chanel Injection (NCTF 135HA) was the luxurious wellness drink for the skin. The formula combined vitamins, amino acids, minerals, coenzymes, nucleic acids, and hyaluronic acid into one injectable cocktail. Its appeal was immediate: instead of focusing only on regeneration, it promised hydration, whitening, and skin vitality.

Strengths:

• Comprehensive nutrient blend

• Excellent for improving brightness and skin tone

• Provides hydration through hyaluronic acid

Limitations:

• Limited regenerative effect compared to PDRN

• Results can be temporary, requiring frequent sessions

• More of a “skin glow” treatment than a structural repair solution

Patients loved the instant radiance, but doctors knew it lacked the deeper impact of PDRN or collagen stimulators. Chanel Injection made skin look alive, but it didn’t necessarily heal.

Exosomes: The Future of Regenerative Medicine

Then came the word that changed the industry: Exosomes. These nano-sized vesicles, secreted by stem cells, function as messengers of cellular communication. They carry proteins, lipids, and genetic material, enabling them to stimulate regeneration, reduce inflammation, and improve overall skin health.

In aesthetic medicine, exosomes are seen as the future of anti-aging, wound healing, and even hair restoration. Unlike vitamins or DNA fragments, they work by reprogramming how skin cells behave.

Strengths:

• Advanced regenerative and anti-inflammatory properties

• Powerful in repairing and rejuvenating skin at a cellular level

• Represents the “cutting edge” of biotechnology

Limitations:

• Still relatively new and not fully standardized

• Costs can be high

• Regulatory challenges in some countries

For patients, exosomes sound futuristic and exciting. But the question remains: are they enough on their own? Often, exosomes are combined with other treatments to achieve more rounded results.

Juvelook: Collagen Booster for Long-Term Lifting

While exosomes sparked the imagination, Juvelook focused on a practical, long-term concern: collagen loss. Built on PDLLA (Poly-D, L-Lactic Acid) combined with hyaluronic acid, Juvelook works as a biostimulatory filler. Rather than just adding volume, it stimulates the body to produce new collagen over time. The result? Improved lifting, firmness, and structural integrity of the skin.

Strengths:

• Strong collagen stimulation

• Long-lasting lifting and firming effects

• Excellent for sagging and aging skin

Limitations:

• Less effective for whitening, hydration, or anti-inflammatory needs

• Requires careful technique

• Results develop gradually rather than instantly

Patients who wanted structural change loved Juvelook. But those hoping for immediate radiance, hydration, or anti-inflammatory benefits often combined it with other treatments.

The Patient’s Dilemma: Four Choices, One Problem

By now, you can see the dilemma patients and practitioners face:

• Rejuran heals, but does not brighten.

• Chanel Injection brightens, but does not regenerate.

• Exosomes regenerate, but lack standardization.

• Juvelook lifts, but does not hydrate or whiten.

So, patients often end up asking: “Do I really need to choose just one? Why can’t there be one product that does it all?”

This is exactly the question that MAXellize sought to answer with CHX400 and CPX300.

MAXellize CHX400 & CPX300: The All-in-One Premium Boosters

Imagine taking the strengths of Rejuran, Chanel Injection, Exosomes, and Juvelook, and combining them into one formula. That is essentially what CHX400 and CPX300 represent.

Their formulations are built on PDRN, Exosomes, Peptides, Amino Acids, Vitamins, and Hyaluronic Acid, making them true multi-dimensional boosters.

Key Features:

• Regeneration (PDRN + Exosomes): Repairs and restores skin tissue at the cellular level

• Hydration & Radiance (Hyaluronic Acid + Vitamins): Improves glow, brightness, and moisture balance

• Structural Support (Peptides + Amino Acids): Stimulates collagen, improves elasticity and firmness

• Anti-Inflammatory Action: Reduces redness, soothes irritation, supports sensitive skin

In other words, CHX400/CPX300 are not “competitors” to the older products, but their natural evolution.

Clinical Applications

Doctors and clinics are already finding creative uses for CHX400 and CPX300:

• Post-laser recovery: Thanks to PDRN and exosomes, patients heal faster with reduced downtime.

• Anti-aging protocols: Combines lifting, hydration, and radiance in one treatment.

• Sensitive skin patients: The zero-irritation formula (tested 0.00 irritation index) makes it safe even for delicate skin.

• Holistic treatments: Instead of stacking Rejuran, Chanel, and Juvelook separately, practitioners can streamline protocols with CHX400/CPX300.

Market Impact

The rise of CHX400/CPX300 reflects a bigger trend: patients no longer want fragmented solutions. Just as multi-tasking serums replaced 10-step skincare routines, multi-dimensional boosters are replacing one-dimensional injectables.

Clinics benefit as well. With CHX400/CPX300, they can:

• Simplify treatment menus

• Offer premium, differentiated solutions

• Improve patient satisfaction with fewer sessions

Conclusion: The Story Comes Full Circle

If Rejuran was the beginning of skin regeneration, Chanel Injection was the age of vitality, Exosomes the age of cellular communication, and Juvelook the age of collagen lifting—then MAXellize CHX400 and CPX300 represent the era of integration.

They do not reject their predecessors, but rather honor them by combining their strengths into one. For patients, this means less confusion, less cost, and better results. For clinics, it means innovation and competitiveness.

In the story of skin boosters, CHX400 and CPX300 are not just the next chapter—they are the book that ties the chapters together.